Add egg to a large mixing bowl and whisk.
Add in breadcrumbs, romano cheese, garlic powder, onion powder, salt, pepper, and dried parsley and mix well.
Add in ground beef and mix together, making sure to not overwork the meat.
Roll into 1 1/2 inch meat balls.
In a 12 inch cast iron skillet, add oil and let get very hot, but not yet smoking on medium high heat.
Add in the meatballs, making sure to not overcrowd, and brown meatballs on each side for 3-4 minutes. I normally do this step in 2 batches.
Remove meatballs from the skillet and let rest, don't worry if they aren't fully cooked yet.